Extraordinary competitor turned government agent Xander Cage (Vin Diesel) leaves willful outcast, thought to be long dead, and is determined to a crash course with lethal alpha warrior Xiang (Donnie Yen) and his group in a race to recoup a vile and apparently relentless weapon known as Pandora's Box. Enlisting an all-new gathering of excite looking for accomplices, Xander gets himself enmeshed in a dangerous scheme that focuses to plot at the most abnormal amounts of world governments.

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